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In the psoriatic epidermis, S100A12 is expressed in the suprabasal epidermal layers (133), and its expression levels correlate positively with psoriasis severity (134)
For example, in macrophages, the activation of NF-B in response to LPS stimulation leads to the production of proinflammatory cytokines e.g., TNF- and interleukin-6 (IL-6), which are important for the initiation and regulation of the immune response [130]
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(1999) provided a comprehensive review of these gastroprotective findings, documenting consistent results across more than 20 distinct experimental lesion models (Sikiric et al., 1999, Journal of Physiology Paris
EBM Consult
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus
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